Lopez won the fight by technical knockout in the second round at Madison Square Garden, New York, USA.
Lopez (15-0, 12 KO) punched and dropped Commey (29-3, 26 KO) to the floor with a right hand. Commey was floored when the two boxers threw punches at the same time but Lopez hit Commey first, landing a blow that dropped the champion to the canvas. Commey managed to get back to his feet, but Lopez followed up with a flurry of punches; as Commey was unable to reply, the referee stepped in and stopped the fight in the second round.
Following this win, the 22-year-old Lopez is set to fight Vasiliy Lomachenko in a unification bout in April 2020.